Synthesis of (2β,3α,6-2H3)cholesteryl linoleate and cholesteryl oleate as internal standards for mass spectrometry
详细信息 查看全文
- 作者：Yusuke Miuraa ; Shu-Ping Huia ; keino@hs.hokudai.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Rojeet Shresthaa ; Takahisa Hirumaa ; Seiji Takedaa ; Hirotoshi Fudaa ; Shigeo Ikegawaa ; Ken-ichi Hiranob ; c ; Hitoshi Chibaa
- 关键词：mp ; melting points ; 1H NMR ; proton nuclear magnetic resonance ; DEPT ; distortionless enhancement by polarization transfer ; EI ; Electron ionization ; LR-MS ; low-resolution mass spectra ; HR-MS ; high-resolution mass spectra ; EI ; electrospray ionization ; DMAP ; N ; N&prime ; -dimethylaminopyridine ; THF ; tetrahydrofuran ; rDA ; retro Diels&ndash ; Alder ; EDCI ; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide
- 刊名：Steroids
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：107
- 期：Complete
- 页码：1-9
- 全文大小：855 K
文摘
- ass="listitem" id="list_l0005">
- ass="label">•
We establish synthetic routes of (2β,3α,6-2H3)cholesteryl linoleate and cholesteryl oleate as internal standard for LC/MS.
- ass="label">•
The structural assignment of synthetic compounds is confirmed by NMR and MS spectra.
- ass="label">•
The isotopic purities of the labeled compounds are estimated to be satisfactory by MS.