Asymptomatic progressive multifocal leukoencephalopathy during natalizumab therapy with treatment
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- 作者：Marzena J. Fabis-Pedrinia ; 1 ; Wen Xua ; b ; 1 ; Jason Burtona ; William M. Carrolla ; Allan G. Kermodea ; c ; kermode@me.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Immune reconstitution inflammatory syndrome ; Multiple sclerosis ; Natalizumab ; Progressive multifocal leukoencephalopathy
- 刊名：Journal of Clinical Neuroscience
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：25
- 期：Complete
- 页码：145-147
- 全文大小：347 K
文摘
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We report a case of asymptomatic progressive multifocal leukoencephalopathy (PML) detected on regular MRI screening.
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The initial MRI detection of PML was both atypical and subtle.
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Pre-emptive treatment was associated with a benign PML course and outcome.
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Changes on MRI during natalizumab treatment may suggest PML as a possible cause.