Base controlled (1,1)- and (1,2)-hydrophosphination of functionalized alkynes

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• 作者：Yi Zhang ; Lulu Tang ; Yi Ding ; Jia-Hui Chua ; Yongxin Li ; Mingjun Yuan ; Pak-Hing Leung
• 关键词：Gemini surfactants ; Antimicrobial ; Quaternary ammonium groups ; MIC
• 刊名：Tetrahedron Letters
• 出版年：2008
• 出版时间：10 March 2008
• 年：2008
• 卷：49
• 期：11
• 页码：1762-1767
• 全文大小：330 K

文摘

The (1,1)- and (1,2)-addition of diphenylphosphine to 3-butyn-2-one and ethyl propiolate can be controlled chemoselectively by regulating the amount of triethylamine as the external base and in the presence of the chiral organopalladium(II) template derived from (R)-N,N-dimethyl-1-(1-naphthyl)ethylamine.