Nucleus incertus (NI), source of relaxin-3, regulates stress and feeding behaviours.
Inputs from orexin-A neuron populations to the nucleus incertus are convergent.
Orexin-A positive fibres make appositions to relaxin-3-positive NI neurons.
Orexin-A excites relaxin-3 and other neurons of the nucleus incertus.
NI neurons express mainly OX2 receptors.