Study of Lewis acid accelerated palladium catalyzed CH activation

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• 作者：Orsolya Tischler^a ; Szabolcs Ková ; cs^a ; Gá ; bor É ; rsek^a ; Pé ; ter Krá ; ll^a ; Já ; nos Daru^b ; Andrá ; s Stirling^b ; ^{stirling.andras@ttk.mta.hu} ; Zoltá ; n Nová ; k^a ; ^{novakz@elte.hu}
• 关键词：CH activation ; palladium ; Lewis acid ; DFT studies
• 刊名：Journal of Molecular Catalysis A: Chemical
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：426
• 期：part_PB
• 页码：444-450
• 全文大小：1696 K
• 卷排序：426

文摘

Amide and urea directed ortho-acylation and ortho-olefination on aromatic cores is accelerated by Lewis acidic additives. Lewis acidic additives afford more electrophilic transition metal center, favoring CH activation. The efficiency of several palladium(II) catalysts is raised. KIE experiments and calculations suggests a rate-determining CH activation step.