Environmental exposure to human carcinogens in teenagers and the association with DNA damage

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• 作者：Carmen Franken^a ; ^b ; ^{carmen.franken@vito.be} ; Gudrun Koppen^a ; Nathalie Lambrechts^a ; Eva Govarts^a ; Liesbeth Bruckers^c ; Elly Den Hond^a ; ¹ ; Ilse Loots^d ; Vera Nelen^e ; Isabelle Sioen^f ; ^g ; Tim S. Nawrot^h ; ⁱ ; Willy Baeyens^j ; Nicolas Van Larebeke^j ; ^k ; Francis Boonen^a ; Danië ; lla Ooms^a ; Mai Wevers^a ; Griet Jacobs^a ; Adrian Covaci^l ; Thomas Schettgen^m ; Greet Schoeters^a ; ^b ; ⁿ
• 刊名：Environmental Research
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：152
• 期：Complete
• 页码：165-174
• 全文大小：476 K
• 卷排序：152

文摘

Exposure to (potential) carcinogens is associated with (oxidative) damage to DNA. Most associations of exposures are with urinary 8-OHdG. 1-Hydroxypyrene and chromium are associated with the comet assay and 8-OHdG. PFOA is associated with higher levels of DNA damage in the alkaline comet assay.