Monitoring γ-glutamyl transpeptidase activity and evaluating its inhibitors by a water-soluble near-infrared fluorescent probe
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- 作者：Lihong Li ; Wen Shi ; shiwen@iccas.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Xiaofeng Wu ; Qiuyu Gong ; Xiaohua Li ; Huimin Ma
- 关键词：γ-Glutamyl transpeptidase ; Near-infrared fluorescent probe ; Water-soluble fluorescent probe ; Inhibitors
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 July 2016
- 年：2016
- 卷：81
- 期：Complete
- 页码：395-400
- 全文大小：684 K
文摘
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The first near-infrared fluorescent probe is developed for γ-glutamyl transpeptidase.
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The probe has an emission wavelength over 700 nm with high selectivity and sensitivity.
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The probe exhibits excellent water-solubility.
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The probe is used to image γ-glutamyl transpeptidase activity in zebrafish.