Aptamer functionalized hydrophilic polymer monolith with gold nanoparticles modification for the sensitive detection of human α-thrombin
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- 作者：Yuanbo Chena ; b ; Nan Denga ; b ; Ci Wua ; b ; Yu Lianga ; Bo Jianga ; Kaiguang Yanga ; Zhen Lianga ; Lihua Zhanga ; lihuazhang@dicp.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Yukui Zhanga
- 关键词：Aptamer ; Hydrophilic monolith ; Human α-thrombin ; Trace protein detection
- 刊名：Talanta
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：154
- 期：Complete
- 页码：555-559
- 全文大小：1169 K
文摘
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Aptamer functionalized monolith with AuNPs modification was prepared.
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The monolithic column was homogeneous and with stable structure.
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High selectivity and high recovery for target protein were achieved.
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The α-thrombin in human plasma was detected with high sensitivity.