Modification of cut-off values for HE4, CA125 and the ROMA algorithm for early-stage epithelial ovarian cancer detection: Results from 1021 cases in South China
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- 作者：Ying Xua ; b ; 1 ; Rihui Zhonga ; b ; 1 ; Jian Hea ; b ; Rui Dinga ; b ; Haixiong Lina ; b ; Yawen Denga ; b ; Lijun Zhoua ; b ; Xiaohui Lic ; Junyi Jianga ; b ; Yunwen Baoa ; b ; Xiaohong Luoa ; b ; Chaohui Duana ; b ; 1725012289@qq.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：EOC ; epithelial ovarian cancer ; HE4 ; human epididymis protein 4 ; ROMA ; risk of ovarian malignancy algorithm ; ROC ; receiver operator characteristic curve ; AUC ; area under the receiver operator characteristic curve
- 刊名：Clinical Biochemistry
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：49
- 期：1-2
- 页码：32-40
- 全文大小：796 K
文摘
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HE4 is a better predictor of malignancy than is CA125 in patients with a pelvic mass.
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HE4 provides for improved diagnosis of early-stage EOC of over CA125.
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An alternate cutoff value of HE4 was obtained by analyzing 1021 cases in South China.