A dual-label time-resolved fluorescence immunoassay (TRFIA) for screening of Coronary atherosclerosis based on simultaneous detection of Lp-PLA₂ and HsCRP

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• 作者：Zhong Zhang^a ; ¹ ; ^{2658165389@qq.com} ; Xiaozhu Liu^b ; ¹ ; Yinfeng Li^b ; Ruolan Huang^c ; Ling Wang^c ; Laiqing Li^d ; Cuicui Chen^d ; Lijun Ou^a ; Xiao Chang^c ; Qiujie Qiao^c ; Mingtai Chen^c
• 关键词：Dual-label TRFIA ; LP-PLA2 ; hsCRP ; Coronary atherosclerosis
• 刊名：Immunology Letters
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：182
• 期：Complete
• 页码：12-17
• 全文大小：991 K
• 卷排序：182

文摘

Atherosclerosis is the underlying cause of most coronary events, and the conventional detection methods are complex and time-consuming. Here, a two-step dual-label TRFIA was developed for the simultaneous detection of Lp-PLA2 and hsCRP in a single run. The present dual-label TRFIA is sensitive, simple and inexpensive, and is a good alternative to the single-label diagnostic methods.