Early Commissural Diencephalic Neurons Control Habenular Axon Extension and Targeting

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• 作者：Carlo A. Beretta¹ ; ² ; ³ ; Nicolas Dross² ; ³ ; ¹² ; Luca Guglielmi¹ ; ¹² ; Peter Bankhead² ; Marina Soulika⁴ ; ⁵ ; ⁶ ; Jose A. Gutierrez-Triana⁷ ; ⁸ ; Alessio Paolini¹ ; ⁸ ; Lucia Poggi⁸ ; ⁹ ; Julien Falk¹⁰ ; Soojin Ryu⁷ ; ¹¹ ; Marika Kapsimali⁴ ; ⁵ ; ⁶ ; Ulrike Engel² ; ³ ; ⁸ ; Matthias Carl¹ ; ¹³ ; ^{matthias.carl@medma.uni-heidelberg.de}
• 关键词：habenula ; zebrafish ; asymmetry ; axon elongation ; commissures ; time lapse ; neural network ; thalamus ; brain
• 刊名：Current Biology
• 出版年：2017
• 出版时间：23 January 2017
• 年：2017
• 卷：27
• 期：2
• 页码：270-278
• 全文大小：4089 K
• 卷排序：27

文摘

Bilateral habenular axons extend synchronously despite differing neuronal birth dates Diencephalic neurons ipsilaterally control the initiation of habenular axon extension A commissural network coordinates habenular axon extension across hemispheres Habenular axons require the intersecting diencephalic network to reach their target