Evaluation of direct and indirect ethanol biomarkers using a likelihood ratio approach to identify chronic alcohol abusers for forensic purposes

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• 作者：Eugenio Alladio^a ; ^b ; ^{ealladio@unito.it} ; ^{eugenio.alladio@gmail.com} ; Agnieszka Martyna^c ; ^{ag.rzepecka@gmail.com} ; Alberto Salomone^b ; ^{alberto.salomone@antidoping.piemonte.it} ; Valentina Pirro^d ; ^{vpirro@purdue.edu} ; Marco Vincenti^a ; ^b ; ^{marco.vincenti@unito.it} ; Grzegorz Zadora^c ; ^e ; ^{gzadora@ies.krakow.pl}
• 关键词：Alcohol ; Likelihood ratio ; Empirical cross entropy ; EtG ; FAEE ; Hair analysis
• 刊名：Forensic Science International
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：271
• 期：Complete
• 页码：13-22
• 全文大小：1002 K
• 卷排序：271

文摘

Detection of alcohol misuse conditions is made possible by multivariate likelihood ratios approaches. Linear Discriminant Analysis in combination with likelihood ratio strategies are used to discriminate chronic from non-chronic alcohol drinkers. Anomalous cases related to several factors (e.g. hair treatments) can be detected, too. The present proof-of-concept approach might corroborate the conclusions of the traditional interpretation approach suggested by the Society of Hair Testing.