- 作者：Paula Bompastor-Ramos ; MD ; MSc ; Joã ; o Pó ; voa ; MD ; Conceiç ; ã ; o Lobo ; MD ; PhD ; Alejandra E. Rodriguez ; MSc ; Jorge L. Alió ; MD ; PhD ; Liliana Werner ; MD ; PhD ; Joaquim N. Murta ; MD ; PhD ; jmurta@netcabo.pt" class="auth_mail" title="E-mail the corresponding author
- 刊名：Journal of Cataract & Refractive Surgery
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：42
- 期：9
- 页码：1324-1331
- 全文大小：1280 K
Setting
Department of Ophthalmology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Design
Retrospective case series.
Methods
Medical records were reviewed of patients with Lentis LS-502-1 IOL opacification reporting visual loss who had IOL explantation between November 2013 and March 2015. Patients were identified in the emergency room or during regular follow-up visits. Explanted IOLs were analyzed at the Ophthalmic Explants Biobank, Vissum, Spain, or at the John A. Moran Eye Center, University of Utah, USA.
Results
Twenty opacified IOLs were explanted from 19 patients. The mean interval between cataract surgery and diagnosis of opacification was 29.15 months ± 9.57 (SD) (range 6 to 45 months). Opacification led to a statistically significant reduction in corrected distance visual acuity (mean 0.86 ± 0.76 logMAR; P < .001) and occurred in 5.1% of the hydrophilic–hydrophobic acrylic IOLs implanted at the department. The most frequently associated medical conditions were arterial hypertension, diabetes, and glaucoma. All IOLs but 1 had a similar pattern of opacification, with yellowish diffuse opacification uniformly distributed and calcium deposits on the surface and/or subsurface of the optic and haptics and within the IOL material.
Conclusions
Opacification of the hydrophilic–hydrophobic acrylic IOL was found in a significant number of patients and had a significant effect on their vision. The opacification was attributed to primary calcification.
Financial Disclosure
None of the authors has a financial or proprietary interest in any material or method mentioned.