Development and application of micro-polysaccharide drug carriers incorporating doxorubicin and superparamagnetic iron oxide for bimodality treatment of hepatocellular carcinoma
We report a simple method for preparing DOX-SPIO-CS/CHI MPs using electrospray. The formulation exhibits better ability against both Caucasian and Mongoloid cancer cells. The IC50 value of DOX-SPIO-CS/CHI MPs was half of the value of free DOX (0.12 nM).