Melatonin-loaded silica coated with hydroxypropyl methylcellulose phthalate for enhanced oral bioavailability: Preparation, and in vitro-in vivo evaluation
刊名:European Journal of Pharmaceutics and Biopharmaceutics
出版年:2017
出版时间:March 2017
年:2017
卷:112
期:Complete
页码:58-66
全文大小:839 K
卷排序:112
文摘
The silica loaded with melatonin, and then coated with HP55. The release of melatonin was markedly increased in vitro study. The bioavailability of MLT-SiO2-HP55 was 3.5 times as raw melatonin.