Secondary neurotransmitter deficiencies in epilepsy caused by voltage-gated sodium channelopathies: A potential treatment target?
详细信息 查看全文
- 作者：Gabriella A. Horvatha ; Michelle Demosb ; Casper Shyrc ; d ; Allison Matthewsc ; d ; Linhua Zhangc ; Simone Racea ; Sylvia Stockler-Ipsiroglua ; Margot I. Van Allend ; Ogan Mancarcie ; Lilah Tokere ; Paul Pavlidise ; Colin J. Rossd ; Wyeth W. Wassermanc ; d ; Natalie Trumpf ; Simon Healesg ; h ; Simon Popeg ; J. Helen Crossi ; Clara D.M. van Karnebeeka ; c ; cvankarnebeek@cw.bc.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：Seizures ; Channelopathy ; SCN2A ; SCN8A ; Nav1.2 ; Nav1.6 ; Dopamine ; Serotonin ; Therapy
- 刊名：Molecular Genetics and Metabolism
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：117
- 期：1
- 页码：42-48
- 全文大小：531 K
文摘
- m" id="list_l0005">
- •
1st report of neurotransmitter abnormalities in
- •
Description of response to neurotransmitter supplementation in SCN2A deficiency case
- •
Hypothesis to explain relation between channelopathy, seizures, abnormal 5HIAA & HVA