Circulating activin A is a novel prognostic biomarker in malignant pleural mesothelioma - A multi-institutional study
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- 作者：Mir Alireza Hodaa ; b ; Yawen Donga ; Anita Rozsasa ; c ; Thomas Klikovitsa ; Viktoria Laszloa ; Bahil Ghanima ; Paul Stockhammera ; Judit Ozsvara ; Marko Jakopovicd ; Miroslav Samarzijad ; Luka Brcice ; Matyas Bendekc ; Ildiko Szirtesf ; Glen Reidg ; Michaela B. Kirschnerg ; Steven C. Kaog ; Isabelle Opitzh ; Walter Wederh ; Thomas Frauenfelderi ; Thi Dan Linh Nguyen-Kimi ; Clemens Aignerm ; Walter Klepetkoa ; Nico van Zandwijkg ; Walter Bergerb ; Balazs Domea ; c ; j ; k ; Michael Gruschb ; Balazs Hegedusa ; k ; l ; balazs.hegedus@meduniwien.ac.at" class="auth_mail" title="E-mail the corresponding author
- 关键词：Malignant pleural mesothelioma ; Activin A ; Biomarker ; Prognosis
- 刊名：European Journal of Cancer
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：63
- 期：Complete
- 页码：64-73
- 全文大小：843 K
文摘
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Plasma activin A levels are increased in malignant pleural mesothelioma (MPM) patients.
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Increased levels associated with non-epithelioid morphology and high tumour volume.
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Plasma activin A level was an independent prognostic factor in MPM patients below 66 years of age with an epithelioid histology.