文摘
Five new compounds, named ancistronaphtosides A and B (1 and 2), anciscochine (3), anciscochine 6-m>Om>-β-mallcaps">d-glucopyranoside (4), and 4′-methoxy-5-m>epim>-ancistecrorine A1 (5), together with tortoside A (6) and 4-hydroxy-2-methoxyphenyl-6-m>Om>-syringoyl-β-mallcaps">d-glucopyranoside (7) were isolated from the methanolic extract of m>Ancistrocladus cochinchinensism>. Their chemical structures were established using HR-ESI-MS, NMR spectroscopic, and chiroptical methods. Compound 5 significantly exhibited anti-proliferation against HL-60, LU-1, and SK-MEL-2 cells with IC50 values of 5.0 ± 1.2, 6.5 ± 1.6, and 6.8 ± 2.0 μg/mL, respectively.