Antifungal activity, mode of action and anti-biofilm effects of Laurus nobilis Linnaeus essential oil against Candida spp.

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• 作者：Larissa Rangel Peixoto^a ; Pedro Luiz Rosalen^b ; Gabriela Lacet Silva Ferreira^a ; Irlan Almeida Freires^b ; Fabí ; ola Galbiatti de Carvalho^a ; Lú ; cio Roberto Castellano^a ; ^c ; Ricardo Dias de Castro^a ; ^{ricardodiasdecastro@pq.cnpq.br}
• 关键词：Candidiasis ; Oral ; Antifungal agents ; Candida ; Oils ; Volatile ; Laurus nobilis
• 刊名：Archives of Oral Biology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：73
• 期：Complete
• 页码：179-185
• 全文大小：502 K
• 卷排序：73

文摘

This study approaches the antibiofilm potential of Laurus nobilis essential oil (EO). The EO inhibited Candida spp. biofilm adhesion and formation. L. nobilis EO affects the yeast cell wall and membrane ionic permeability. Chemical analysis identified isoeugenol as the major compound. Further toxicological studies should confirm its potential applicability in dentistry.