- 作者：Thierry Gevaert ; M.Sc. ; thierry.gevaert@uzbrussel.be ; Dirk Verellen ; Ph.D. ; Koen Tournel ; M.S. ; Nadine Linthout ; Ph.D. ; Samuel Bral ; M.D. ; Benedikt Engels ; M.D. ; Christine Collen ; M.D. ; Tom Depuydt ; I.R. ; Michael Duchateau ; M.Sc. ; Truus Reynders ; M.Sc. ; Guy Storme ; M.D. ; Ph.D. ; Mark De Ridder ; M.D. ; Ph.D.
- 关键词：Radiosurgery ; Frameless image guide positioning ; Frame-based positioning ; Overall accuracy
- 刊名：International Journal of Radiation Oncology*Biology*Physics
- 出版年：2012
- 出版时间：1 April, 2012
- 年：2012
- 卷：82
- 期：5
- 页码：1627-1635
- 全文大小：512 K
Purpose
Stereotactic radiosurgery using frame-based positioning is a well-established technique for the treatment of benign and malignant lesions. By contrast, a new trend toward frameless systems using image-guided positioning techniques is gaining mainstream acceptance. This study was designed to measure the detection and positioning accuracy of the ExacTrac/Novalis Body (ET/NB) for rotations and to compare the accuracy of the frameless with the frame-based radiosurgery technique.Methods and Materials
A program was developed in house to rotate reference computed tomography images. The angles measured by the system were compared with the known rotations. The accuracy of ET/NB was evaluated with a head phantom with seven lead beads inserted, mounted on a treatment couch equipped with a robotic tilt module, and was measured with a digital water level and portal films. Multiple hidden target tests (HTT) were performed to measure the overall accuracy of the different positioning techniques for radiosurgery (i.e., frameless and frame-based with relocatable mask or invasive ring, respectively).
Results
The ET/NB system can detect rotational setup errors with an average accuracy of 0.09¡ã (standard deviation [SD] 0.06¡ã), 0.02¡ã (SD 0.07¡ã), and 0.06¡ã (SD 0.14¡ã) for longitudinal, lateral, and vertical rotations, respectively. The average positioning accuracy was 0.06¡ã (SD 0.04¡ã), 0.08¡ã (SD 0.06¡ã), and 0.08¡ã (SD 0.07¡ã) for longitudinal, lateral and vertical rotations, respectively. The results of the HTT showed an overall three-dimensional accuracy of 0.76 mm (SD 0.46 mm) for the frameless technique, 0.87 mm (SD 0.44 mm) for the relocatable mask, and 1.19 mm (SD 0.45 mm) for the frame-based technique.
Conclusions
The study showed high detection accuracy and a subdegree positioning accuracy. On the basis of phantom studies, the frameless technique showed comparable accuracy to the frame-based approach.