Quality standardization of herbal medicines using effective compounds combination as labeled constituents
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- 作者：Long Guo ; Li Duan ; Li-Li Dou ; Le-Le Liu ; Hua Yang ; E-Hu Liu ; liuehu2011@163.com" class="auth_mail" title="E-mail the corresponding author ; Ping Li ; liping2004@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Effective compounds combination ; Quality standardization ; Tanshinones extract ; Herbal medicines
- 刊名：Journal of Pharmaceutical and Biomedical Analysis
- 出版年：2016
- 出版时间：10 September 2016
- 年：2016
- 卷：129
- 期：Complete
- 页码：320-331
- 全文大小：3511 K
文摘
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The effective compounds combination (ECC) responsible for the cardioprotective efficacy of tanshinones extract (TE) was discovered.
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The pharmacokinetics of single tanshinone compound, ECC and TE were studied comparatively.
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A quality standardization of TE was established based on ECC using single standard for determination of multiple components method.