Cellular models for the evaluation of the antiobesity effect of selected phytochemicals from food and herbs

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• 作者：Yen-Chen Tung^a ; Pei-Hsuan Hsieh^b ; Min-Hsiung Pan^a ; ^c ; ^d ; ^{mhpan@ntu.edu.tw} ; Chi-Tang Ho^b ; ^{ho@aesop.rutgers.edu}
• 关键词：3T3-L1 cells ; adipogenesis ; lipogenesis ; lipolysis ; phytochemicals
• 刊名：Journal of Food and Drug Analysis
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：25
• 期：1
• 页码：100-110
• 全文大小：1267 K
• 卷排序：25

文摘

Obesity is an important health issue and energy imbalance is a major cause of obesity. The 3T3-L1 preadipocyte is a well-established model to investigate the process of adipogenesis, lipogenesis, lipolysis, oxidation of fatty acids, and browning. Dietary phytochemicals have been studied for their antiobesity effects by regulated adipogenesis, lipogenesis, lipolysis, oxidation of fatty acids, and browning in adipocytes. Dietary phytochemicals could be candidates for treatment of obesity.