Prevalence and pattern of dyslipidemia in hyperglycemic patients and its associated factors among Pakistani population

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• 作者：Maliha Sarfraz^a ; ^{maliha.sarfraz@uaf.edu.pk" class="auth_mail" title="E-mail the corresponding author} ; Sanaullah Sajid^a ; Muhammad Aqeel Ashraf^b ; ^c
• 关键词：Hyperglycemia ; Dyslipidemia ; Prevalence ; Complication of diabetes
• 刊名：Saudi Journal of Biological Sciences
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：23
• 期：6
• 页码：761-766
• 全文大小：505 K

文摘

In diabetes mellitus dyslipidemia is one of the major risk factors for cardiovascular disease. In type 2 diabetes mellitus early detection and treatment of dyslipidemia can avoid risk for cardiovascular disorder. The present study was carried to determine the prevalence and pattern of hyperlipidemia in patients with hyperglycemia. The cross sectional study was done in different laboratories of Pakistan, the laboratories served patients referred from different government and private hospitals between July 2014 and June 2015. All known cases of diabetes mellitus were evaluated for their lipid profile. Totally 200 diabetic patients were included in the study in which 120 (60%) were males and 80 (40%) were females. Prevalence of dyslipidemia among diabetic males was 97.18% while for females 87.15%. Among dyslipidemic male the proportion with mixed dyslipidemic patients was 17.5%, combined two parameters dyslipidemia was 47.5% and isolated single parameter dyslipidemia was 35%. In females these proportions in mixed, combined two parameters and isolated single parameter were 16.25%, 51.25% and 32.5%, respectively. Majority of hyperglycemic patients were dyslipidemic. The most prevalent pattern among male was combined dyslipidemia with high triglycerides (TG) and low High Density Lipoprotein (HDL) and in female it was high Low Density Lipoprotein (LDL) and low HDL. The most prevalent lipid abnormality in our study was low HDL followed by high TG.