Preliminary investigation of the relationships between sleep duration, reward circuitry function, and mood dysregulation in youth offspring of parents with bipolar disorder
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- 作者：Adriane M. Soehnera ; 1 ; soehneram2@upmc.edu" class="auth_mail" title="E-mail the corresponding author ; Michele A. Bertoccia ; 1 ; Anna Manelisa ; Genna Bebkoa ; Cecile D. Ladouceura ; Simona Graura ; Kelly Monka ; Lisa K. Bonara ; Mary Beth Hickeya ; David Axelsonb ; Benjamin I. Goldsteinc ; Tina R. Goldsteina ; Boris Birmahera ; Mary L. Phillipsa
- 关键词：Bipolar disorder risk ; Sleep ; Reward processing ; Functional MRI
- 刊名：Journal of Affective Disorders
- 出版年：2016
- 出版时间：15 November 2016
- 年：2016
- 卷：205
- 期：Complete
- 页码：144-153
- 全文大小：1954 K
文摘
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Offspring of bipolar parents (OBP) exhibit altered reward circuitry function.
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Sleep duration predicts altered activity and striatal connectivity to wins in OBP.
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Sleep duration is related to mood dysregulation in OBP.
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Striatal connectivity is related to mood dysregulation in OBP.
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Altered striatal connectivity may link sleep loss to mood dysregulation in OBP.