Cerebral dopamine neurotrophic factor alleviates Aβ25-35-induced endoplasmic reticulum stress and early synaptotoxicity in rat hippocampal cells
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- 作者：Wei Zhou ; Lirong Chang ; Yuan Fang ; Zunshu Du ; Yan Li ; Yizhi Song ; Fei Hao ; Liying Lv ; Yan Wu ; yanwu@ccmu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; wuyan73@yahoo.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：CDNF ; Amyloid-beta ; Synapse ; ER stress ; Hippocampus ; Alzheimer&rsquo ; s disease
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：28 October 2016
- 年：2016
- 卷：633
- 期：Complete
- 页码：40-46
- 全文大小：2714 K
文摘
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ER stress could be triggered by Aβ treatment at early stage in primary neurons.
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CDNF alleviates Aβ-induced early synaptotoxicity.
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CDNF protects against Aβ-induced ER stress.