TBT is still a common pollutant in freshwaters and ecotoxicological data is needed.
The planarian Schmidtea mediterranea showed sensitivity to low TBT concentrations.
TBT exposure impaired locomotion and feeding activity of S. mediterranea.
Delayed regeneration and genotoxicity were observed in planarians exposed to TBT.
Freshwater planarians are suitable for a wide range of ecotoxicological tests.