Comparison of methods to quantify posterior capsule opacification using forward and backward light scattering

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• 作者：Nino Hirnschall ; MDAuthor Vitae ; Alja Crnej ; MD ; FEBO ; Vinod Gangwani ; MRCOphth ; Oliver Findl ; MD ; MBA ; ^{oliver@findl.at" class="auth_mail}
• 刊名：Journal of Cataract and Refractive Surgery
• 出版年：May 2014
• 年：2014
• 卷：40
• 期：5
• 页码：728-735
• 全文大小：761 K

文摘

To compare forward and backward light scattering measurements to quantify posterior capsule opacification (PCO).

Setting

Vienna Institute for Research in Ocular Surgery, Vienna, Austria.

Design

Prospective single-center study.

Methods

This observational study comprised consecutive patients scheduled for neodymium:YAG (Nd:YAG) capsulotomy for regeneratory PCO. The corrected distance visual acuity (CDVA) using Early Treatment of Diabetic Retinopathy Study charts and the contrast sensitivity under mesopic and photopic conditions using Pelli-Robson charts were assessed before an Nd:YAG capsulotomy was performed. Retroillumination images, rotating Scheimpflug scans (Pentacam HR), and straylight meter (C-Quant) and point-spread function (PSF) meter (Optical Quality Analysis System) measurements were performed before and after Nd:YAG capsulotomy.

Results

The study enrolled 50 eyes of 50 patients. The mean uncorrected distance visual acuity and CDVA were 0.76 logMAR ± 0.18 (SD) and 0.68 ± 0.2 logMAR, respectively. The mean log contrast sensitivity (logCS) was 1.2 ± 0.15 logCS under photopic conditions and 1.05 ± 0.15 logCS under mesopic conditions. There was a moderate correlation between the Scheimpflug score and the Automated Quantification of After-Cataract score (r² = 0.37, P=.03). Furthermore, a moderate and close to significant correlation between the PSF meter and the straylight meter was observed (r² = 0.32; P=.07).

Conclusion

Each of the 4 devices assesses different aspects of a patient's quality of vision. Further developments should focus on methods that measure forward scatter of light in a large visual angle and are not too patient or examiner dependent.

Financial Disclosure

No author has a financial or proprietary interest in any material or method mentioned.