Epitheliotropic Gastrointestinal T-Cell Lymphoma With Concurrent Insulinoma and Adrenocortical Carcinoma in a Domestic Ferret (Mustela putorius furo)

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• 作者：Kristin M. Sinclair ; DVM ; Dip. ABVP (Avian)^a ; Chrissy Eckstrand ; DVM^a ; Peter F. Moore ; BVSc ; PhD^c ; Michelle G. Hawkins ; VMD ; Dip. ABVP (Avian)^b ; ^{mghawkins@ucdavis.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：T-cell lymphoma ; insulinoma ; adrenocortical carcinoma ; ferret ; lomustine
• 刊名：Journal of Exotic Pet Medicine
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：25
• 期：1
• 页码：34-43
• 全文大小：4049 K

文摘

A 5-year-old male castrated ferret was presented for evaluation of chronic diarrhea, unresponsive to medical therapy. Initial examination and minimum database findings failed to determine an underlying etiology for the ferret’s gastrointestinal disorder. Biopsies obtained by exploratory surgery confirmed a diagnosis of epitheliotropic gastrointestinal T-cell lymphoma. Several treatment strategies were discussed, and ultimately palliative care with prednisolone was elected. Over the course of treatment, the ferret developed concurrent pancreatic beta-cell adenomas (insulinoma) and a left adrenocortical carcinoma. At the time of necropsy, nearly 15 months after the exploratory surgery, the lymphoma appeared to be in regression despite the use of only palliative therapy.