CRISPR-Cas: Spacer Diversity Determines the Efficiency of Defense

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• 作者：Anna Lopatina ; Rotem Sorek ; ^{rotem.sorek@weizmann.ac.il" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Current Biology
• 出版年：2016
• 出版时间：25 July 2016
• 年：2016
• 卷：26
• 期：14
• 页码：R683-R685
• 全文大小：1427 K

文摘

Bacterial CRISPR–Cas systems acquire short sequences, called spacers, from viruses and plasmids, leading to adaptive immunity. The diversity of spacers within natural bacterial populations is very high. New data now explain how spacer diversity strengthens resistance of the bacterial population to phage infection.