Sensitivity of breast MRI for ductal carcinoma in situ appearing as microcalcifications only on mammography

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• 作者：Pierluigi Rinaldi ; Chiara Buccheri ; ^{chiara.buccheri@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Michela Giuliani ; Enida Bufi ; Maurizio Romani ; Federica Patrolecco ; Paolo Belli ; Lorenzo Bonomo
• 关键词：Ductal carcinoma in situ (DCIS) ; Microcalcifications ; Mammography ; DCE MRI ; DWI MRI
• 刊名：Clinical Imaging
• 出版年：2016
• 出版时间：November-December 2016
• 年：2016
• 卷：40
• 期：6
• 页码：1207-1212
• 全文大小：533 K

文摘

This study aims to investigate sensitivity of breast magnetic resonance imaging (MRI) for mammographic microcalcifications-only ductal carcinoma in situ (DCIS), based on its histopathology and mammographic extent of microcalcifications.

Methods

Mammograms were reviewed to measure the extent of microcalcifications. Sensitivity of MRI was calculated in the overall study population and in groups differing for DCIS nuclear grade, microinvasivity, and microcalcifications' extent.

Results

Overall sensitivity of MRI was 78.3% for dynamic contrast enhanced and 66.7% for diffusion-weighted imaging and did not vary with nuclear grade and microinvasivity, while it increased with larger extent of microcalcifications (ExpB=1.063–1.046, P=.037–.013).

Conclusions

Mammographic extent of microcalcifications positively affects sensitivity of breast MRI.