Prenatal lead exposure and fetal growth: Smaller infants have heightened susceptibility

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• 作者：Rodosthenis S. Rodosthenous^a ; ^{rrodosth@hsph.harvard.edu} ; Heather H. Burris^a ; ^b ; ^{heburris@bidmc.harvard.edu} ; Katherine Svensson^c ; ^{Katherine.svensson@mssm.edu} ; Chitra J. Amarasiriwardena^c ; ^{Chitra.amarasiriwardena@mssm.edu} ; Alejandra Cantoral^d ; ^{alejandra.cantoral@insp.mx} ; Lourdes Schnaas^d ; ^{lschnaas@hotmail.com} ; Adriana Mercado-Garc&iacute ; a^d ; ^{adrianam@insp.mx} ; Brent A. Coull^a ; ^{bcoull@hsph.harvard.edu} ; Robert O. Wright^c ; ^{Robert.wright@mssm.edu} ; Martha M. Té ; llez-Rojo^d ; ^{mmtellez@insp.mx} ; Andrea A. Baccarelli^e ; ^{andrea.baccarelli@columbia.edu}
• 关键词：Lead ; Fetal growth ; Birth weight ; Small-for-gestational age ; Pregnancy ; Quantile regression
• 刊名：Environment International
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：99
• 期：Complete
• 页码：228-233
• 全文大小：359 K
• 卷排序：99

文摘

Evidence on the association between prenatal lead exposure and fetal growth is inconsistent. Elevated lead levels were associated with lower birthweight and increased odds of small-for-gestational age birth. Quantile regression revealed that infants with poor fetal growth are more susceptible to the effects of lead. We encourage the use of quantile regression when assessing the impact of prenatal lead exposure on fetal growth.