p73 Is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network
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- 作者：Clayton B. Marshall1 ; 7 ; Deborah J. Mays1 ; 7 ; J. Scott Beeler1 ; Jennifer M. Rosenbluth1 ; 2 ; Kelli L. Boyd3 ; 4 ; Gabriela L. Santos Guasch1 ; Timothy M. Shaver1 ; Lucy J. Tang1 ; Qi Liu5 ; Yu Shyr4 ; 5 ; Bryan J. Venters4 ; 6 ; Mark A. Magnuson4 ; 6 ; Jennifer A. Pietenpol1 ; 4 ; j.pietenpol@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：15 March 2016
- 年：2016
- 卷：14
- 期：10
- 页码：2289-2300
- 全文大小：4847 K
文摘
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p73 is required for murine MCC differentiation
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MCC loss provides a unifying biological defect for phenotypes in p73−/− mice
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p73 binds to the genome in proximity to 105 cilia-associated genes, including Foxj1
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p73 directly regulates and is required for Foxj1 expression