Complex and interacting influences of the autonomic nervous system on cardiac electrophysiology in conscious mice
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- 作者：Heidi L. Lujan
- 关键词：Sympathetic ; Parasympathetic ; Wenckebach cycle length ; Sinus node recovery time ; Atrio-ventricular interval ; Electrocardiogram
- 刊名：Autonomic Neuroscience: Basic and Clinical
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：201
- 期：Complete
- 页码：24-31
- 全文大小：677 K
文摘
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- <p id="p0005">The Sympatho-Vagal Balance index documents a slight parasympathetic dominance of cardiac electrophysiology in conscious mice.p>
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- <p id="p0010">Thus, resting cardiac autonomic balance of conscious mice is more similar to that of humans than originally reported.p>
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- <p id="p0015">The concept of accentuated antagonism of heart rate and cardiac electrophysiology parameters applies to conscious mice.p>
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- <p id="p0020">This is important, especially in view of the ever increasing use of this animal species in cardiovascular research.p>
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- <p id="p0025">Pharmacological agents used for cardiac disorders have varying effects depending on the background level of autonomic tone.p>