Advanced portrayal of SMIL coating by allying CZE performance with in-capillary topographic and charge-related surface characterization

详细信息    查看全文

• 作者：Lorenz G. Stock^a ; ^b ; ¹ ; Michael Leitner^c ; ¹ ; Lukas Traxler^c ; Klaus Bonazza^d ; Laurent Leclercq^e ; Herv&eacute ; Cottet^e ; Gernot Friedbacher^d ; Andreas Ebner^c ; Hanno Stutz^a ; ^b ; ^{hanno.stutz@sbg.ac.at}
• 关键词：Atomic force microscopy ; Capillary zone electrophoresis ; Protein separation ; SMIL coating ; Square capillary ; Topography and recognition imaging
• 刊名：Analytica Chimica Acta
• 出版年：2017
• 出版时间：25 January 2017
• 年：2017
• 卷：951
• 期：Complete
• 页码：1-15
• 全文大小：4611 K
• 卷排序：951

文摘

SMIL coating with a terminal layer of reduced charge density improves CZE separation. Capillaries with rectangular diameter allow for in-capillary TREC-AFM measurement. CZE performance is related to topography and charge distribution on the SMIL surface. Topographic changes are confirmed by statistical methods.