Subclinical impairment of lung function is related to mild cardiac dysfunction and manifest heart failure in the general population
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- 作者：Christina Bauma ; 1 ; c.baum@uke.de" class="auth_mail" title="E-mail the corresponding author ; Francisco M. Ojedaa ; Philipp S. Wildb ; c ; 2 ; Nargiz Rzayevaa ; 1 ; Tanja Zellera ; 1 ; Christoph R. Sinninga ; Norbert Pfeifferd ; Manfred Beutele ; Maria Blettnerf ; Karl J. Lacknerg ; 2 ; Stefan Blankenberga ; 1 ; Thomas Mü ; nzelh ; 2 ; Klaus F. Rabei ; Renate B. Schnabela ; 1 ; for the Gutenberg Health Study investigators
- 关键词：BMI ; body mass index ; CAD ; coronary artery disease ; COPD ; chronic obstructive pulmonary disease ; EDV ; end-diastolic volume ; EF ; left ventricular ejection fraction ; ESV ; end-systolic volume ; FEV1 ; forced expiratory volume in 1 ; s ; FVC ; forced vital capacity ; HF ; heart failure ; HFpEF ; heart failure with preserved ejection fraction ; HFrEF ; heart failure with reduced ejection fraction ; hsTnI ; high-sensitive troponin I ; IVSd ; interventricular end-diastolic septum diameter ; LVESd ; left ventricular
- 刊名：International Journal of Cardiology
- 出版年：2016
- 出版时间：1 September 2016
- 年：2016
- 卷：218
- 期：Complete
- 页码：298-304
- 全文大小：819 K
文摘
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Already mild impairment of pulmonary function is related to cardiac biomarkers of necrosis and stress.
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Subtle alterations in lung function are associated with systolic and diastolic dysfunction and manifest heart failure.
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These associations remain statistically significant even after exclusion of individuals with clinically manifest COPD.