Measuring inputs to a common function: The case of Dlx5 and Dlx6
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- 作者：Anna Quach ; Rachel K. MacKenzie ; Andrew J. Bendall ; abendall@uoguelph.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：Dlx5 ; Dlx6 ; Functional equivalence ; Paralog ; Transcription factor
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：9 September 2016
- 年：2016
- 卷：478
- 期：1
- 页码：371-377
- 全文大小：1103 K
文摘
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Dlx5 is expressed at higher levels than Dlx6 in chicken embryos.
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Dlx5 and Dlx6 are quantitatively indistinguishable in a heterologous cellular context.
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Dlx6 is a stronger transactivator than Dlx5 in cells in which they have co-evolved.