Severe and benign Plasmodium vivax malaria in Emberá (Amerindian) children and adolescents from an endemic municipality in Western Colombia

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• 作者：Diego A. Medina-Morales^a ; ^b ; ^c ; Estefaní ; a Montoya-Franco^a ; Viviana d.P. Sanchez-Aristizabal^a ; Jorge E. Machado-Alba^a ; ^d ; Alfonso J. Rodrí ; guez-Morales^b ; ^e ; ^f ; ^{arodriguezm@utp.edu.co" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Malaria ; Plasmodium vivax ; Pediatrics ; Epidemiology ; Colombia
• 刊名：Journal of Infection and Public Health
• 出版年：2016
• 出版时间：March-April 2016
• 年：2016
• 卷：9
• 期：2
• 页码：172-180
• 全文大小：975 K

文摘

Malaria in children is still an important public health problem in endemic areas of South-East Asia and Latin America. Certain forms of the disease, such as Plasmodium vivax severe malaria, are still neglected. This descriptive study assessed the frequency of severe and benign P. vivax infection in Emberá children (<14 years of age) from an endemic municipality in Colombia in 2013, using the WHO criteria. During 2013, 270 Emberá children presented 349 episodes of malaria. From them, 22 (8.1%) presented at least one of the criteria for severe malaria. Some patients with P. vivax presented with severe malaria (severe anemia, renal dysfunction, respiratory distress and seizure). Mixed malaria cases presented more complications than those with monoinfection (OR = 5.535; 95%CI 1.81–16.9). In Colombia, few data are available about severe P. vivax malaria in children, especially in the Amerindian ethnic groups. Mixed infections were associated with increased risk of severe malaria. At the same time, detailed and prospective studies are needed to measure the real impact of severe vivax malaria, as was evidenced in this paper.