Fusiform Aneurysms Are Associated with Aortic Root Dilatation in Patients with Subarachnoid Hemorrhage

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• 作者：Anil Can¹ ; ³ ; ⁴ ; Jun Xu¹ ; ⁵ ; Victor Volovici⁴ ; Ruben Dammers⁴ ; Clemens M.F. Dirven⁴ ; Calum A. MacRae² ; ³ ; Rose Du¹ ; ³ ; ^{rdu@partners.org" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Aortic root diameter ; Aortopathy ; Fusiform ; Intracranial aneurysm
• 刊名：World Neurosurgery
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：84
• 期：6
• 页码：1681-1685
• 全文大小：1595 K

文摘

Aortic root dimension (ARD), an echocardiographic marker of aortopathy, has recently been associated with intracranial aneurysm eccentricity, suggesting a common underlying pathophysiology between intracranial aneurysm and aortopathy.

Objective

To identify specific intracranial aneurysm-related parameters that independently correlate with ARD in patients with subarachnoid hemorrhage.

Methods

Clinical and aneurysm-related parameters obtained from 151 patients with ruptured intracranial aneurysms, and who also underwent echocardiography with ARD measured, were examined. Univariate and multivariate analysis were performed to determine correlation of these parameters with ARD.

Results

151 patients who were evaluated from 2008 to 2013 were analyzed. Multivariate linear regression revealed that male gender and fusiform aneurysms were correlated with higher ARD (P < 0.01 and P = 0.041, respectively) after adjustment for other morphological and clinical variables.

Conclusions

Fusiform aneurysms are correlated with larger ARD than saccular aneurysms, suggesting a shared pathophysiologic mechanism with aortopathy.