Perihepatitis associated with pelvic inflammatory disease or Fitz-Hugh-Curtis syndrome is an inflammatory process that involves the liver capsule and adjacent peritoneum and is related to pelvic infections due to Chlamydia trachomatis and Neisseria gonorrhoeae. Diagnosis may be difficult because the clinical picture is nonspecific, especially when manifestations of pelvic inflammatory disease are scarce or absent. In the last few years, computed tomography has been shown to be a highly useful and non-invasive diagnostic procedure in the proper clinical context. We present two cases of perihepatitis associated with pelvic inflammatory disease, diagnosed with computed tomography.