- 作者：Cari Pé ; rez-Vives ; PhD ; cari.perez@uv.es" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae ; Teresa Ferrer-Blasco ; PhD ; Alejandro Cerviñ ; o-Expó ; sito ; PhD ; David Madrid-Costa ; PhD ; Robert Monté ; s-Micó ; PhD
- 刊名：Journal of Cataract & Refractive Surgery
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：41
- 期：10
- 页码：2266-2273
- 全文大小：1300 K
Setting
University of Valencia, Valencia, Spain.
Design
Experimental study.
Methods
Wavefront aberrations in −3.00 D and −6.00 diopter (D) pIOLs were measured in vitro. Afterward, different simulated pIOL experimental prototypes were created along with variances in the spherical aberration. An adaptive optics visual simulator was used to simulate vision after the implantation of the different pIOL prototypes from their wavefront aberrations. The corrected distance visual acuity (CDVA) and depth of focus were measured in 3.0 and 4.5 mm pupils.
Results
In a 3.0 mm pupil, the CDVA achieved with −3.00 and −6.00 D pIOLs and all pIOL prototypes evaluated was above 20/20 except for a −6.00 D pIOL + spherical aberration 4 at 50% CDVA contrast, which decreased to 20/25. However, in a 4.5 mm pupil, the CDVA obtained with the pIOL prototypes decreased significantly and was more pronounced when the spherical aberration induced was negative. The depth of focus increment was larger with the highest spherical aberration added and with a small pupil. Nevertheless, it was independent of the sign of the added spherical aberration.
Conclusions
The outcomes show that residual negative spherical aberration after pIOL implantation will disrupt the CDVA. However, some residual positive spherical aberration after pIOL implantation increased the depth of focus with excellent CDVA, providing a possible pIOL design for young presbyopic patients.
Financial Disclosure
No author has a financial or proprietary interest in any material or method mentioned.