i.p. 50 mg/kg Guo decreased the number of spike-wave discharges (SWDs).
i.p. 100 mg/kg Guo enhanced the number of SWDs in WAG/Rij rats.
Effect of 100 mg/kg Guo was inhibited by theophylline, SCH 58261 and indomethacin.
i.p. 100 mg/kg Guo may increase SWD number by means of adenosinergic system.