Clinical impact of prostate specific antigen (PSA) inter-assay variability on management of prostate cancer
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- 作者：Vedang Murthya ; vmurthy@actrec.gov.in" class="auth_mail" title="E-mail the corresponding author ; Anupam Rishia ; Sanjeev Guptab ; Sadhana Kannanc ; Umesh Mahantshettya ; Hemant Tongaonkard ; Ganesh Bakshid ; Kumar Prabhashe ; Paresh Bhanushalib ; Bhoopal Shindef ; Nitin Inamdarf ; Shyamkishore Shrivastavaa
- 关键词：Prostate specific antigen ; PSA assays ; Variability ; Clinical impact ; Passing Bablok
- 刊名：Clinical Biochemistry
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：49
- 期：1-2
- 页码：79-84
- 全文大小：884 K
文摘
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The study evaluates PSA inter-assay variability among six commercial assays.
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Significant inter-assay variability and poor agreement
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Variability most among ELISA based assays
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Assay discrepancies have a profound impact on important clinical decisions.
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Chances of ‘risk group’ migration and misinterpretation of biochemical failure