Phytochemical screening and in vitro bioactivities of the extracts of aerial part of Boerhavia diffusa Linn.

详细信息    查看全文

• 作者：Apurba Sarker Apu ; ^{apurba2sarker@yahoo.com} ; Mahmuda Sultana Liza ; A.T.M. Jamaluddin ; Md. Amran Howlader ; Repon Kumer Saha ; Farhana Rizwan ; Nishat Nasrin
• 关键词：Boerhavia diffusa ; Antioxidant ; Cytotoxic ; Thrombolytic ; Antimicrobial ; DPPH ; NO
• 刊名：Asian Pacific Journal of Tropical Biomedicine
• 出版年：2012
• 出版时间：September, 2012
• 年：2012
• 卷：2
• 期：9
• 页码：673-678
• 全文大小：322 K

文摘

Objective

To investigate the bioactivities of crude n-hexane, ethyl acetate and methanol extracts of aerial part of Boerhavia diffusa Linn. (B. diffusa) and its phytochemical analysis.

Methods

The identification of phytoconstituents and assay of antioxidant, thrombolytic, cytotoxic, antimicrobial activities were conducted using specific standard in vitro procedures.

Results

The results showed that the plant extracts were a rich source of phytoconstituents. Methanol extract showed higher antioxidant, thrombolytic activity and less cytotoxic activity than those of n-hexane and ethyl acetate extracts of B. diffusa. Among the bioactivities, antioxidant activity was the most notable compared to the positive control and thus could be a potential rich source of natural antioxidant. In case of antimicrobial screening, crude extracts of the plant showed remarkable antibacterial activity against tested microorganisms. All the extracts showed significant inhibitory activity against Candida albicuns, at a concentration of 1 000 ¦Ìg/disc.

Conclusions

The present findings suggest that, the plant widely available in Bangladesh, could be a prominent source of medicinally important natural compounds.