Digestion by pepsin releases biologically active chromopeptides from C-phycocyanin, a blue-colored biliprotein of microalga Spirulina
详细信息 查看全文
- 作者：Simeon L. Minica ; Dragana Stanic-Vucinica ; Jelena Mihailovica ; Maja Krstica ; Milan R. Nikolica ; b ; Tanja Cirkovic Velickovica ; b ; tcirkov@chem.bg.ac.rs" class="auth_mail" title="E-mail the corresponding author
- 关键词：C-phycocyanin ; Phycocyanobilin ; Digestibility ; Peptides ; Bioactivity
- 刊名：Journal of Proteomics
- 出版年：2016
- 出版时间：16 September 2016
- 年：2016
- 卷：147
- 期：Complete
- 页码：132-139
- 全文大小：944 K
文摘
- •
C-Phycocyanin, blue biliprotein of Spirulina, is rapidly digested by pepsin.
- •
Sequences of peptic chromopeptides were determinated by tandem mass spectrometry.
- •
Antioxidant, metal-chelating and cytotoxic effect on cancer cell lines were shown.
- •
Chromopeptides protect human erythrocytes from free radical-induced hemolysis.
- •
Chromophore is mainly responsible for observed biological effects of chromopeptides