The mitogenic activity of the liver growth factor is mediated by tumor necrosis factor alpha in rat liver

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• 作者：Dí ; az-Gil ; Juan J. ; Majano ; Pedro L. ; Ló ; pez-Cabrera ; Manuel ; Sá ; nchez-Ló ; pez ; Vicente ; et. al.
• 关键词：Liver growth factor ; Tumor necrosis factor-α ; GdCl ; gadolinium chloride ; PCNA ; proliferating cell nuclear antigen ; PH ; partial hepatectomy ; LGF ; liver growth factor ; TNF-α ; tumor necrosis factor alpha ; HUVEC ; human umbilical vein endothelial cel
• 刊名：Journal of Hepatology
• 出版年：2003
• 出版时间：May, 2003
• 年：2003
• 卷：38
• 期：5
• 页码：598-604
• 全文大小：521 K

文摘

Background/Aims: Liver growth factor (LGF) is a hepatic mitogen, however, the hepatic stimulation pathway remains to be characterized. The aim of this study was to determine whether tumor necrosis factor alpha (TNF-α) stimulation constitutes a step in the mitogenic pathway of LGF.