Preliminary MALDI-TOF-MS analysis of seminal plasma N-glycome of infertile men

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• 作者：Anna Kałużap>ap> ; Anna Jarząbp>cp> ; Andrzej Gamianp>bp>p> ; p>p>cp> ; Ewa M. Kratzp>ap> ; Mariusz Zimmerp>dp> ; Mirosława Ferens-Sieczkowskap>ap>p> ; p>p>miroslawa.ferens-sieczkowska@umed.wroc.pl" class="auth_mail" title="E-mail the corresponding authorp>
• 关键词：MALDI-TOF-TOF-MS/MS ; Male infertility ; N-glycome ; Seminal plasma ; Fetoembryonic defence
• 刊名：Carbohydrate Research
• 出版年：2016
• 出版时间：29 November 2016
• 年：2016
• 卷：435
• 期：Complete
• 页码：19-25
• 全文大小：1508 K

文摘

<dl class="listitem" id="list_ulist0010"><dt class="label">•dt><dd><p id="p0010">Seminal plasma N-glycome studied with MALDI-TOF-MS was compared in fertile and infertile men.p>dd><dt class="label">•dt><dd><p id="p0015">In asthenozoospermic SP the content of highly fucosylated glycans was elevated while their sialylation was decreased.p>dd><dt class="label">•dt><dd><p id="p0020">The content of highly branched glycans was increased in normozoospermic infertile men.p>dd><dt class="label">•dt><dd><p id="p0025">Alterations of seminal plasma N-glycome are associated with male infertility.p>dd>dl>