Single and combined genotoxicity effects of six pollutants on THP-1 cells
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- 作者：Dan Xiaoa ; b ; Haiyan Wanga ; wanghaiyan@tio.org.cn" class="auth_mail" title="E-mail the corresponding author ; Daxiong Hanb ; daxiong@xmu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Colorants ; Acrylamide ; Bromate ; Genotoxic effect ; Comet assay ; Food safety
- 刊名：Food and Chemical Toxicology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：95
- 期：Complete
- 页码：96-102
- 全文大小：2089 K
文摘
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The tested synthetic colorants contributed to greater DNA damage than acrylamide or potassium bromate.
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Chrysoidine G mixed with Sudan I, malachite green, acrylamide, or potassium bromate had significant genotoxic effects.
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It is necessary to set more reasonable food security evaluation standards by considering ubiquitously combined exposure.