A case of falciparum malaria: Acute hearing loss as the initial symptom

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• 作者：Takeshi Tada^a ; Akihiro Hitani^b ; Natsue Hosono Honda^b ; Shinichi Haruna^c ; Tsuyoshi Yoshimura^a ; Kosuke Haruki^b ; Yasuhiro Tanaka^a ; ^{tanakay@dokkyomed.ac.jp}
• 关键词：Cerebral malaria ; Deafness ; ABR ; MRI
• 刊名：Journal of Infection and Chemotherapy
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：23
• 期：1
• 页码：56-58
• 全文大小：586 K
• 卷排序：23

文摘

A 49-year-old healthy woman, who returned from Burkina Faso, visited an ear, nose, and throat clinic with complaints of left hearing loss, tinnitus, and dizziness. Pure tone audiometry demonstrated bilateral mild sensorineural hearing loss. Three days later, she was transported in an ambulance to a general hospital due to high fever and disturbance of consciousness. Plasmodium falciparum was found in the peripheral blood smear. After diagnosing severe falciparum malaria with cerebral involvement, quinine hydrochloride, clindamycin, and artemether/lumefantrine were administered. After recovery of consciousness, she was followed up at our department with bilateral hearing loss. After taking prednisolone for 10 days, there was improvement to normal hearing level. Furthermore, no neurologic sequelae were observed.In this case, acute sensorineural hearing loss occurred before administration of the antimalarial drug. Therefore, hearing loss was not drug-induced, but was caused by the malaria itself. In patients with acute hearing loss and who have history of travel to tropical regions, physicians should include malaria and other causes of acute deafness in the differential diagnoses.