Exposure to environmentally relevant concentrations of malathion induces significant cellular, biochemical and histological alterations in Labeo rohita
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- 作者：Subrata Karmakar ; Kartick Patra ; Samarjit Jana ; Deba Prasad Mandal<sup> ; sup><sup>dpmandal1972@gmail.com" class="auth_mail" title="E-mail the corresponding authorsup> ; Shamee Bhattacharjee<sup> ; sup><sup>shamee1405@gmail.com" class="auth_mail" title="E-mail the corresponding authorsup>
- 关键词：Malathion ; sub-lethal ; oxidative stress ; histopathology ; cytotoxicity
- 刊名：Pesticide Biochemistry and Physiology
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：126
- 期：Complete
- 页码：49-57
- 全文大小：1191 K
文摘
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Impact of environmentally significant concentration of malathion on Rohu fingerlings.
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HPLC analysis of serum samples confirmed the bioavailability of malathion in fish.
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Malathion inhibited brain acetylcholinesterase activity dose-dependently.
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Malathion induces oxidative stress in gill, liver and kidney.
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Cell cycle analysis of the above organs revealed cellular injury.
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Histopatholgical lesions were observed in gills, liver and kidney.