MALDI-TOF mass spectrometry for rapid diagnosis of postoperative endophthalmitis

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• 作者：Adriane Mailhac^a ; Harmonie Durand^b ; Sandrine Boisset^c ; Daniè ; le Maubon^d ; ^e ; Francois Berger^b ; Max Maurin^c ; Christophe Chiquet^a ; Marie Bidart^b ; ^f ; ^g ; ^{MBidart@chu-grenoble.fr}
• 关键词：MALDI-TOF mass spectrometry ; Vitreous ; Endophthalmitis ; Blood culture ; Direct identification ; Staphylococcus
• 刊名：Journal of Proteomics
• 出版年：2017
• 出版时间：30 January 2017
• 年：2017
• 卷：152
• 期：Complete
• 页码：150-152
• 全文大小：245 K
• 卷排序：152

文摘

This study describes an innovative strategy for rapid detection and identification of bacteria causing endophthalmitis, combining the use of an automated blood culture system with MALDI-TOF mass spectrometry methodology. Using this protocol, we could identify 96% of 45 bacterial strains isolated from vitreous samples collected in acute post-operative endophthalmitis patients.